Prevent CDI-55
About the Project
Clostridioides difficile infection (CDI) is the most common cause of severe, infectious diarrhea in hospitalized patients. It is estimated that each CDI case costs Alberta $9,610-$32,400 per hospitalization, a total annual burden of $12-28 million. Probiotics are live microorganisms that promote healthy gut flora and have been studied as a possible measure to prevent CDI. The Prevent CDI-55 quality improvement initiative aims to reduce the incidence of hospital-acquired CDI by prescribing probiotics with antibiotics to hospitalized patients over the age of 55.
Impact
- Evaluation of the overall incidence of hospital-acquired CDI in patients over the age of 55, in the pre- vs. post-intervention periods of prescribing the probiotic BioK+ with therapeutic antibiotics
- Implementing a practice change in four Calgary hospitals by prescribing probiotics with antibiotics
- Measuring resource use and costs associated with the introduction of probiotics and conducting a cost-effectiveness analysis to evaluate the value of probiotics to the healthcare system
Services Provided
- Grant Writing Support
- Ethics Development and Management
- Clinical Trial Design and Coordination
- Medical and Scientific Oversight
- Regulatory Applications and Submissions
- Participant Screening and Recruitment
- Specimen Collection
- Data Management
- Stakeholder Engagement
- Knowledge Translation
Additional Content
